Qwen 3.5 397B-A17B — H200 vs MI325X Performance per Dollar
Cost per million tokens of H200 (NVIDIA Hopper) versus MI325X (AMD CDNA 3) on Qwen 3.5 397B-A17B. Owning-hyperscaler TCO normalized by output tokens — performance per dollar across LLM workloads. Pick the more cost-efficient SKU at every target interactivity level. Use the chart controls below to switch sequences, precisions, and metrics — same interactions as the main inference chart.
At 46 tok/s/user on Qwen 3.5 397B-A17B, H200 costs $0.56 per million tokens; MI325X costs $0.74. H200 is 33% more cost-efficient at this operating point.
H200 edges MI325X at 55 tok/s/user on Qwen 3.5 397B-A17B — $0.61 per million tokens versus $1.40, a 129% cost-per-token gap.
Push Qwen 3.5 397B-A17B to 64 tok/s/user and H200 lands at $0.66 per million tokens against MI325X's $2.27 — H200 pulls ahead by 241%. (Numbers reflect the default 1k/1k · fp8 selection for this URL — table and chart below update if you change sequence, precision, or model in the controls.)
Chip pricing (owning hyperscaler): H200 $1.22/chip/hr · MI325X $1.10/chip/hr. Source: SemiAnalysis Market July 2026 Pricing Surveys & AI Cloud TCO Model.

| Metric | Interactivity (tok/s/user) | Interactivity (tok/s/user) | Interactivity (tok/s/user) |
|---|---|---|---|
| Dollar per Million Tokens | H200:$0.559MI325X:$0.743 | H200:$0.611MI325X:$1.402 | H200:$0.664MI325X:$2.267 |
| Concurrency | H200:~52MI325X:~37 | H200:~40MI325X:~16 | H200:~32MI325X:~9 |
Inference Performance
Inference performance metrics across different models, hardware configurations, and serving parameters.